10-21-10  Thursday Day -5  (I’m adding the nomenclature used in transplants.  Day 0 will be my transplant day, which is now 5 days away).

Status:  9.5/10.  Feeling quite good. 

Events:  Had my test dose of Bulfan last night, and other than frequent blood draws interrupting my sleep, handled it well.  Started the 4-day regimen this evening with both Fludarabine and Busulfan.  They give the Fludarabine first because they learned that giving Busulfan first caused more instances of liver injury (one of the many things garnered over the years that’s resulted in better outcomes).  They’ll still draw hourly blood samples until tomorrow morning at 8 AM to fine tune the dose.  The nurses apologize for this and the fact that they have to draw the first few samples by needlestick.  The thoughtfulness is appreciated, but it is what it is, so no real reason to apologize.

   I took a couple of long walks with Lisa, and I’ve stayed out of my bed as much as possible.  NASA researchers in order to mimic the deteriorating effects of weightlessness simply put healthy subjects at bed rest for a few weeks.  The deterioration in muscle and bone mass is remarkable.  Not only has the human body evolved to exist on a gravitational planet but we now depend upon it for our welfare. The U.S. and Russia have spent billions on learning how to deal with the weightless environment on long-term space missions, for example to Mars.  Imagine the disaster that would occur if an astronaut steps off his Mars-lander and breaks his weakened leg bone.  A simple solution would be to provide Earth’s normal gravitation for the entire mission.  Not by some magical gravitational field on Star Trek, but by spinning the capsule.  You could spin it at a speed (not necessarily that fast) so that the centrifugal force equaled the Earth’s gravitational force.  There would be an up and a down, and when an astronaut let go of an object it would fall to the floor just as it did before he rocketed into space.  It’s also the principle behind Einstein’s Theory of General Relativity that demonstrates the equivalence of gravity and acceleration.  I figure if it was good enough for Einstein it should be good enough for NASA.

 Comments:   On my first entry to this blog, I entitled it Defying Gravity, which is what I’ve been striving to do these last 6 months.  Our hope is that this last effort will be a culmination of that goal – leaving the land of the sick to the land of the well.  We could not have progressed this far without your love and support. 

 I send that love back to you.

-Bruce

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9 Responses to “”

  1. Esperanza Says:

    Thank you for being You,
    With my love every step of the way
    xxxoooo

  2. Andrea Tuttle Says:

    So far so good. One thing apparent to me from your blog is that there has already been one remarkable outcome and that has been the opportunity to deepen and appreciate bonds, the connections to your family and the people who love you the most. Those healing relationships can be counted upon as adjunct therapy. I believe there are a few studies that show all these healing thoughts and prayers as well as touch do expedite healing. Know my mind is holding you and your family in loving place.

  3. wendy Says:

    And history has shown that people have done the most amazing things all in the name of and because of love. With all that love Bruce – you will be sure to do the most amazing things.

  4. Wally Schlech Says:

    Can I say “Blast” off!?

  5. Kathy Shands Says:

    A mch better start than last week! I don’t want to say hang in there, after all that NASA stuff, so stomp in there!
    Love, Kathy

  6. Laurie Samuels Says:

    Glad you are feeling we well as you are… continued love, good wishes, thoughts and prayers are with you daily. Laurie and Harry

  7. joel steinberg Says:

    We are praying that all goes well. Joel and Margaret. P.S. The astronaut would know that he is in an artificial, rotating frame of reference if he dropped an object. The object would not fall in a straight line, but rather would take a curved path due to the Coriolis effect. Only if the spaceship were being linearly accelerated at 9.8 m/sec/sec would the Earth’s gravity be perfectly reproduced. But you are correct: The spinning capsule concept would indeed prevent bone and muscle loss (as seen in 2001: A Space Odyssey) JS

  8. Bill Israel and Eileen Breslin Says:

    Professor Bruce: We continue to appreciate taking in your lessons — didactic, experimental, analytical, and personal. We are enriched by being part of your extended family through the ethers, and anticipate wading through the remaining waters with you, as well. Great to hear you and Lisa out for a walk. -Bill and Eileen

  9. Gail Lehmann Says:

    We are all here in “space” wishing you a successful voyage.
    Gail & Mark

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